Indonesia’s rapidly growing beauty industry has intensified competition among aesthetic clinics, making superior customer satisfaction a critical strategy for competitive advantage. This study examines: (1) the effect of interpersonal communication on customer satisfaction at Hers Aesthetic Clinic; (2) the role of service quality in shaping customer satisfaction at the clinic; and (3) the combined impact of interpersonal communication and service quality on customer satisfaction. The population included all clients who received treatment at Hers Aesthetic Clinic, totaling 3,110 individuals. Sample size was determined using the Slovin formula with a 10% margin of error and 99.6% confidence level, yielding 100 respondents. Purposive sampling was used, with respondents selected based on criteria: (1) registered customers of Hers Aesthetic Clinic; (2) individuals who purchased skincare products and received treatment services; and (3) customers with repeat purchase or treatment experience. Results confirm that interpersonal communication is a positive and significant predictor of customer satisfaction at Hers Aesthetic Clinic (p < 0.001). Service quality also emerges as a significant positive predictor of customer satisfaction (p = 0.001). When tested together, both predictors demonstrate a strong and significant combined effect on customer satisfaction, reflected in the F-statistic (F = 140.237; p < 0.001). The coefficient of determination (R² = 0.743) indicates that 74.3% of variance in customer satisfaction is explained by interpersonal communication and service quality, while the remaining 25.7% is attributed to other factors not included in this study.